ISS Versus R-ISS for Risk Stratification of Multiple Myeloma Patients undergoing Autologous Stem Cell Transplant
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چکیده
منابع مشابه
ISS Versus R-ISS for Risk Stratification of Multiple Myeloma Patients undergoing Autologous Stem Cell Transplant
Rafael Ríos-Tamayo1,2,3,4, Antonio Romero2, José Manuel Puerta2, Pedro Antonio González2, Elisa López-Fernández2, Lucía Moratalla2, Juan Sáinz1,2,3,4, Manuel Jurado1,2,3,4 1Monoclonal Gammopathies Unit, University Hospital Virgen de las Nieves, Granada, Spain 2Department of Hematology, University Hospital Virgen de las Nieves, Granada, Spain 3Genomic Oncology Area, GENYO, Centre for Genomics an...
متن کاملCytogenetics and Revised International Staging System (R-ISS): Risk Stratification in Multiple myeloma - A Retrospective Study in Indian Population
Background & Objective: Cytogenetic abnormalities in Multiple myeloma (MM) has emerged as the most important factor that determine the prognosis and survival. Fluorescence in situ hybridization (FISH) can detect a greater number of cytogenetic abnormalities as compared to conventional karyotyping and hence has become the standard test in determining genetic abnormalities in MM....
متن کاملPost-Autologous (ASCT) Stem Cell Transplant Therapy in Multiple Myeloma
Autologous stem cell transplant (ASCT) is the standard of care in transplant-eligible multiple myeloma patients and is associated with significant improvement in progression-free survival (PFS), complete remission rates (CR), and overall survival (OS). However, majority of patients eventually relapse, with a median PFS of around 36 months. Relapses are harder to treat and prognosis declines wit...
متن کاملComplete response after autologous stem cell transplant in multiple myeloma
We evaluated long-term outcome of patients achieving complete response (CR) after autologous stem cell transplantation (ASCT) for multiple myeloma. Between April 1990 and June 2012 191 patients underwent ASCT. The median age was 53 years (range, 26-68 years), 135 were men. Pretransplant, patients received induction therapy with VAD (vincristine, doxorubicin, dexamethasone; n = 77), novel agents...
متن کاملSingle versus double autologous stem-cell transplantation for multiple myeloma.
BACKGROUND We conducted a randomized trial of the treatment of multiple myeloma with high-dose chemotherapy followed by either one or two successive autologous stem-cell transplantations. METHODS At the time of diagnosis, 399 previously untreated patients under the age of 60 years were randomly assigned to receive a single or double transplant. RESULTS A complete or a very good partial resp...
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ژورنال
عنوان ژورنال: Journal of Leukemia
سال: 2015
ISSN: 2329-6917
DOI: 10.4172/2329-6917.1000189